If untreated, ATAAD has a mortality of 33% within the first 24 h and rises to 50% by the first 48 h. Previous artificial blood vessel cannulationĪTAAD and ATAIMH are life-threatening conditions associated with high mortality due to potentially fatal complications that require timely emergency operations. 64.7% of patients received surgical operation in <8 h from admission to operation. The proportion of hypertension was significantly higher in patients with ATAIMH than in patients with ATAAD (82.3% vs. A history of hypertension was elicited in 68.7% of all patients. Marfan syndrome was present in 6.0% of all patients however, none of Marfan syndrome was detected in ATAIMH patients. The time from the onset of symptom to hospitalization was 2.0 days (0.8–8.0). We expect this analysis will provide further insights into the clinical characteristics of patients with ATAAD and ATAIMH in China and promote a better understanding of the diseases.
Therefore, we evaluated the risk factors, clinical manifestations, management, and in-hospital outcomes of 1712 patients with acute type A aortic dissection (ATAAD) and acute type A intramural hematoma (ATAIMH) based on the Sino-RAD database. Although the symptoms and signs of type A aortic dissection have not changed significantly in the past decade, and Chinese clinicians have made considerable progress in the diagnosis and treatment of the disease, there is still a lack of a large sample study of clinical characteristics for type A aortic dissection in China. The results of our previous study demonstrated that Chinese patients with AAD showed different characteristics from those in Western countries, such as the earlier onset of symptoms, lower proportion of hypertension, and differences in treatment strategies. To better understand AAD in the Chinese population, the first Registry of Aortic Dissection in China (Sino-RAD) was established in 2011 which included 15 cardiovascular centers. In China, the incidence of aortic dissection is increasing, among which type A aortic dissection is one of the main types with a high disability and mortality rate. The International Registry of Acute Aortic Dissection (IRAD) was established in 1996, aiming to evaluate the clinical manifestations, management, and outcomes based on a large sample of patients in multiple centers, so as to improve the understanding of this difficult-to-diagnose disease and provide new ideas for management. Acute aortic dissection (AAD) especially needs more attention. Aortic dissection is a rare and life-threatening disease with high mortality, of which the diagnosis and treatment face great challenges.